Omni Group puts out some really great software. I bought a license when they announced they were going to use a WebCore-based engine, and 5.0 has turned out to be a pretty fantastic browser. Nothing against or wrong with Safari, as that's kind of an entry-level browser with some hidden goodies for pro users.
Workspaces are my favorite new feature. Press F2, and I have my news sites. F6 is the Mac stuff and F3 are the design zines I keep up on. Throw in site-specific preferences and a gorgeous UI, and it's a fantastic browser.