I experienced this issue first-hand. The problem appeared to be with a firmware update that was done during an update to Mojave. When booting a display hooked up to the HDMI port, it would fail to display anything on screen. You had to unplug the monitor cable from the HDMI port, then plug it back in for it to work normally.
I had a 2005FPW Dell monitor, which used the same panel as the 20-inch Cinema Display, that I used with my 2018 Mac mini, using an Apple DVI-to-HDMI adapter. There was nothing wrong with the adapter itself. I then switched to a DVI-to-USB-C cable from that I got off of Amazon, which resolved the issue.
Apple support confirmed the problem, was aware of it, but they didn't consider it worthy of engineering effort to fix, according to the poster who originally discovered the problem, after having spent considerable personal time to work with Apple on a potential fix. I can't speak to the issues that other models may be having, but this was very specific to the HDMI port on the 2018 Mac mini and a certain Mojave update.
I've since moved to a 21.5-inch UltraFine, due to macOS being optimized for high-PPI displays, but do recall the troubles caused by this, because I spent months dealing with it.