hi, i have relied on Firefox Tab Containers to help me not ruin my whole day in ServiceNow. but i've fallen head over heels in love with Arc and had to do some experimenting but an Arc Space with a seperate Arc Profile is silo'ed sufficiently for my purposes. Safari's tab groups in combination with profiles seemed to work as well but i didn't test as closely as Arc.I think uBlock dose the same but Firefox Container it also puts Facebook into a 'container' so it cant leak out and see what your browser is doing elsewhere if you do use Facebook on the web, which I do, I have friend scattered across the world and not all have iPhones oddly enough.
i use AdGuard home running via Docker as the resolver devices get via dhcp, and then i use a TLS encrypted upstream resolver for AdGuard to use at CloudFlare. my gateway (unify dream machine) offers an ad-blocker as well and i've turned it on a few times but i'm more comfortable with AdGuard Home and CloudFlare's anycast resolvers that align with the posture of my homenets personally.