We'll see. I have a feeling these forums will start lighting up like never before with problem reports once HS starts getting installed to the wider audience
They always light up with problem reports.
Anyhow, it works fine for me. I currently have the GM installed on 3 different Mac laptops full time, and two of them don't even officially support HS. My 2017 MacBook is AFPS, and the two non-supported ones (a 2008 MacBook and a 2009 MacBook Pro) are HFS+. I also have it installed on an external drive and tested on my two iMacs, one a 2010 and one a 2017, and it also works fine on those.
So, in my case it works just fine with all of these five machines. If anything, I've had way less problems with High Sierra than I did with an older OS, I believe Lion. I have no Fusion drives in any of my machines, but that's a moot point, because the release version won't allow APFS to be used on Fusion drives anyway.
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The first public beta was a nightmare for me. Random crashes, kernel panics, apps refusing to launch. Basically it made my MB Air unusable to the point where I couldn't even file bug reports. I went back to Sierra for a while until Beta 4 came out and then everything was fine. I've had no issues with any of the beta beyond beta 2. As for install over, or install fresh, it's really whatever works for you. I usually install over and then ever 3 years do a fresh install. Usually enough of my apps have been upgraded by then that it's worth the day or so it takes to do it. It also gives me a good excuse to do major housekeeping and clean up a bunch of crap I no longer need. Your mileage may vary.
Yes, the first public beta sucked. Beta 2 also sucked. But after about beta 4 or so it's been OK, and the GM (Candidate) is pretty solid IMO.